שתלים דנטליים
Multitude of studies has been conducted to reveal the relationship between surface roughness, wettability and osseointegration. It has been reported that the rougher implant surface is associated with more osseointegration. And there is optimum level of surface roughness for the maximum osseointegration. Sandblasting and blast with oxide titanium(TiO2) are the most frequently adopted based on the report that the rougher implant surface is associated with more osseointegration. Since oxide titanium(TiO2) does not give the optimum surface wettability, complex biomaterials is used additionally. A surface treatment was performed to produce hydroxylated/hydrated titanium surfaces with a microstructure identical to either acid-etched, or sand-blasted, large grit and acid-etched substrates, but with hydrophilic characteristics. A potential of hydrophilic surface modifications is to support tissue integration of titanium dental implants.
Regeneration of hemophilicity that allows proteins and cells to reach implant surfaces
without creating voids and defects of biological resources.
Considerably increased recruitment and attachment and accelerated settlement and spread
and reinforced retention of osteogenic cells on Bio-Effect surface.
These enhanced biological events effectively and synergistically lead to a new level of osseointegration
and enable a near maximum bone–implant integration (98.2 % BIC) obtained in
an animal model as opposed to 53 % for as-received implants.
Osseointegration refers to a direct structural and functional connection between ordered, living bone and the surface of a load-carrying implant. Currently, an implant is considered as osseointegrated when there is no progressive relative movement between the implant and the bone with which it has direct contact. A direct bone contact as observed histologically may be indicative of the lack of a local or systemic biological response to that surface. It is therefore proposed that osseointegration is not the result of an advantageous biological tissue response but rather the lack of a negative tissue response. Osseointegration or osteointegration refers to a direct bone-to-metal interface without interposition of non-bone tissue. Branemark has described this concept, as consisting of a highly differentiated tissu Osseointegration is seen as the close contact between bone and implant, and the interest on surface engineering has to be understood as an important and natural trend. The bone response, which means rate, quantity and quality, are related to implant surface properties.
Essentially, the process of osseointegration reflects an anchorage mechanism whereby non-vital components can be reliably incorporated into living bone and which persist under all normal conditions of loading. Currently, an implant is considered as osseointegrated when there is no progressive relative movement between the implant and the bone with which it has direct contact. However, the term osseointegration describes a clinical state that provides for long-term stability.
Hydrophilic surfaces seem to favor the interactions with biological fluids and cells when compared to the hydrophobic , and hydrophilicity is affected by the surface chemical composition. Implant surface properties have long been identified as an important factor to promote osseointegration.Bio-Effect SE-03 In stomatology was studies how nanostructures and wettability influence osseointegration and to defined that the wettability, the nanostructure or both in combination play the key role in improved osseointegration.
The implants of differents surface treatment were researching and results, that:
SLA (regual treatment) was hydrofobic, whereas Bio-effect Active treatment was super-hydrophilic. The hydrophobic samples showed higher carbon contamination levels compared with the hydrophilic samples. After 4 weeks healing time,
BIO-EffectActive implants showed the highest pull-out values, with significantly higher pullout force than SLA. After 8 weeks, the Bio-effectActive implants had the highest pull-out force, significantly higher than SLA. The strongest bone response was achieved with a wettability surface of Bio-Effect Implant (Bio-EffectActive).